We wish everyone a good start into the new lunar year of the ox.
Have a happy, prosperous and above all healthy new lunar year everyone!
Did you know that BudgetSensors® silicon AFM probes are made of single-crystal silicon, which has the exact same crystalline structure as diamond? The orientation of the crystal is always the same. The surface of the AFM cantilever is a (100) plane and the AFM cantilever long axis points in the direction.
#AFMProbes #AtomicForceMicroscopy #Crystallography
EBD8-600A: Semi fab metrology workhorse for extreme HAR trench profiling
https://lnkd.in/gcMfhy3
In the article “Millisecond dynamics of an unlabeled amino acid transporter “ Tina R. Matin, George R. Heath, Gerard H. M. Huysmans, Olga Boudker and Simon Scheuring develop and apply high-speed atomic force microscopy line-scanning (HS-AFM-LS) combined with automated state assignment and transition analysis for the determination of transport dynamics of unlabeled membrane-reconstituted GltPh, a prokaryotic EAAT homologue, with millisecond temporal resolution.
Excitatory amino acid transporters (EAATs) are important in many physiological processes and crucial for the removal of excitatory amino acids from the synaptic cleft.*
In the article “Millisecond dynamics of an unlabeled amino acid transporter “ Tina R. Matin, George R. Heath, Gerard H. M. Huysmans, Olga Boudker and Simon Scheuring develop and apply high-speed atomic force microscopy line-scanning (HS-AFM-LS) combined with automated state assignment and transition analysis for the determination of transport dynamics of unlabeled membrane-reconstituted GltPh, a prokaryotic EAAT homologue, with millisecond temporal resolution.*
Among the bulk and single-molecule techniques, high-speed atomic force microscopy ( HS-AFM ) stands out with its ability to provide real-time structural and dynamical information of single molecules. HS-AFM images label-free molecules under close-to-physiological conditions with ~0.1 nm vertical and ~1 nm lateral imaging resolution. Furthermore, HS-AFM has typically ~100 ms temporal resolution, giving access to structure–dynamics relationship of proteins, though the achievable imaging speed depends on sample characteristics like scan size and surface corrugation.
#SingleMoleculeBiophysics #AminoAcidTransporter #videorateAFM #高速AFMカンチレバー #高速原子力显微镜 #HSAFMLS
https://www.nanoworld.com/blog/millisecond-dynamics-of-an-unlabeled-amino-acid-transporter/
